This is how vaccinated people spread COVID-19


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A key factor in the future outbreak of the epidemic is the role of people who are vaccinated in the spread, as global vaccination continues to rise.

The extent to which infected individuals are exposed to the spread of SARS-CoV-2, including species B.1.617.2 (Delta), is unknown.

In a study conducted in a Texas prison, researchers found that those who were vaccinated were still carrying coronavirus, albeit a small number.

The COVID-19 vaccine has been shown to prevent serious illness and death, but it has not been reported that vaccinators could develop the disease until recently.

The incidence of disease in two homes affected by the recent Delta epidemic in federal prison in Texas was 74 percent; was 93 per cent and 70 per cent among non-vaccinated inmates with vaccines in prisons, respectively.

This study compares the probability of the spread of complete and non-vaccinated individuals over time using reverse transcript-polymerase chain reaction (RT-PCR) and viral traits as transcripts.

Of the 189 eligible individuals, 96 people with SARS-CoV-2 infection volunteered to follow several examples; one of the participants had one well-known test (Ct = 36.2) followed by seven misdiagnosis with no symptoms and no symptoms, hence she was shown to be absent.

In this study, 78 (82 percent) of 95 people received the SARS-CoV-2 vaccine, 15 (16 percent) were not vaccinated, and 2 (percent) received a small number of vaccines but were later selected not to be vaccinated.

The Pfizer vaccine was given to most patients (73 percent) while the Moderna vaccine (18 percent) and Janssen (9 percent) vaccine.

Since the positive results of RT-PCR, there have been no significant changes. In studies with complete vaccination, the median duration of optimal RT-PCR was 13 days, compared with 13 days in those not vaccinated.

In addition, among those with a well-known history of SARS-CoV-2 (non-vaccinated) infections, the time when the final outcome of RT-PCR was 10 days, compared with 13 days in participants who were not diagnosed with the virus. in the past.

The median duration of positivity between complete vaccine recipients was 10 days for Moderna vaccine recipients, 13 days for Pfizer recipients, and 13 days for Janssen vaccine recipients; and thirteen days for participants who received the full vaccination more than 120 days before, compared with 11 days for those who received the vaccine 120 days or less earlier.

The number of days from baseline increased CT from positive RT-PCR models. Ct values ​​in the samples of vaccinated individuals increased from an average of 26.4 on the first day to an average of 32.9 on the 10th day. to an average of 34.5 on the tenth day.

There were no significant changes in Ct behavior and vaccine status throughout the course of the disease after Bonferroni preparation. In addition, once Ct levels were stabilized by vaccine, duration of vaccination, or previously known SARS-CoV-2 infections, no significant differences in Ct behavior were found.

Between people who were fully vaccinated (intermediate: 5 days) and those who did not receive the vaccine, there was no significant difference in the duration of the pest culture.

Participants who received the Moderna vaccine had a lower morbidity than those who received the Pfizer or Janssen vaccine, depending on the risk factors. Despite this, there was no obvious difference in vaccine recipients between Pfizer and Janssen.

When the time of culture-positive was stratified by the time since vaccination or known disease, no statistically significant difference has been found in the length of social status.

Those who had previously been unwell with COVID-19 were the only ones who quit; Their virus remained active for no more than 10 days, regardless of vaccination.

The researchers confirmed that there was no significant difference in the spread of coronavirus between people who are fully vaccinated and those who are not vaccinated.

As a result, regardless of the human immunodeficiency virus, COVID-19 protective measures should be put in place, especially in confined spaces (prisons, hospitals, and nursing homes).

From: https://doi.org/10.1101/2021.11.12.21265796

Image credit: Stock

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